Course Information

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Date(s): 10 June 2008

Online Application Period: 12 May - 9 Jun 2008

Venues: Cheyne Lecture Theatre, Royal College of Surgeons in Ireland, Dublin

Download the course poster


IMPORTANT: This course comprises a lecture element (Day 1) and a practical workshop (Day 2). Please note that there is a limited number of places available for the practical workshop.

You must first apply online here. If you only wish to attend the lecture element of the course (Day 1), this is all what you need to do at this stage.
If you also wish to attend the practical workshop (Day 2), then after applying online, please send an Email to expressing your interest.
Please note that those attending the practical workshop must also attend the lecture element of the course. 


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The analysis of genetic determinants in human disease, particularly in multifactorial conditions such as cardiovascular disease, has advanced markedly in recent years due to the availability of high-density maps of Single Nucleotide Polymorphism (SNP) markers, new insights into human genome structure from the International HapMap Project and novel analytical methods. This course, running over two days, aims to introduce researchers to key strategic considerations in designing and performing gene-mapping studies using SNP markers. It will also provide ‘hands-on’ experience of data analysis.

Day 1 (10 June) will focus on the nature and dynamics of SNP markers in populations, associations between markers due to the haplotype ‘block’ structure of the human genome and public domain resources for gene-mapping studies. Talks on applying these tools to clinical problems and the evolution of populations includes two Plenary Lectures on Epilepsy genomics (Dr Sanjay Sisodiya, University College London Hospital) and Population genomics of human gene [removed]Dr Emmanouil T. Dermitzakis, Wellcome Trust Sanger Institute).

Day 2 (11 June) is designed as a ‘hands-on’ practical workshop that examines resources for selecting SNPs, issues around study design & power and data management, and will give time for some basic analyses of SNP data. Please see here for more information on Day 2.

LECTURE SESSION: Tue 10 June (1000-1800)

1000 Introduction to SNP's
Prof David Croke (RCSI)
 1020 Introduction to and history of gene-disease association studies
Prof Denis Shields (UCD)
 1040 Overview of database resources
Dr Ross McManus (TCD)
 1100 Introduction to study design
Prof Denis Shields (UCD)
 1120 Coffee/Tea break
 1140 Overview of software resources
Dr Anthony Ryan (TCD)  
 1205 Developments in Biobanking
Dr Joe McPartlin (TCD) Abstract
 1220 Next Generation Sequencing Technologies
Dr Derek Morris (TCD)
 1235 High-throughput genotyping platforms & technology
Dr Sean Ennis (UCD)
 1250 Lunch provided
 1340 Keynote lecture: Epilepsy genomics
Prof Sanjay Sisodiya (University College London Hospital)  
 1430 Coeliac genetics: Recent insights from genome wide studies
Dr Ross McManus (TCD)
 1500 Identigen
Dr Ronan Loftus (TCD)
 1530 Coffee/Tea break
 1600 Optimising study design for whole genome association
Dr Gianpiero Cavalleri (RCSI)
 1630 Signatures of Selection
Prof Dan Bradley (TCD)  
 1700 Keynote lecture: Population genomics of human gene expression
Dr Emmanouil T. Dermitzakis (Wellcome Trust Sanger Institute)
 1800 Wine Reception - Sponsored by Affymetrix

Course Coordinators

Prof David Croke (Molecular & Cellular Therapeutics, RCSI)
Dr Ross McManus (Institute of Molecular Medicine, St James's Hospital, TCD)
Prof Denis Shields (UCD Conway Institute of Biomolecular & Biomedical Research)

Course Speakers
Prof Dan Bradley (Smurfit Institute of Genetics, TCD)
Dr Gianpiero Cavalleri (Department of Neurology, RCSI)
Dr Emmanouil T. Dermitzakis (Wellcome Trust Sanger Institute, Hinxton, UK)
Dr Sean Ennis (Our Lady's Hospital for Sick Children and School of Medicine & Medical Science, UCD)
Dr Joe McPartlin (Institute of Molecular Medicine, St James's Hospital, TCD)
Dr Derek Morris (Institute of Molecular Medicine, St James's Hospital, TCD)
Prof Sanjay Sisodiya (University College London Hospital)
Dr Anthony Ryan (Institute of Molecular Medicine, TCD)

 Course Sponsors

Gold Sponsor
Affymetrix is sponsoring
the wine reception on Tuesday


Basic Sponsor


Online Application has closed.